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For confirmed B12 deficiency without neurological involvement , the standard regimen comprises 1 mg hydroxocobalamin intramuscularly three times weekly for two weeks, followed by maintenance doses every two to three months for those with irreversible causes like pernicious anaemia

In the present study, the cecal microbiome differed significantly across treatment groups, despite tightly controlling for several variables known to alter the microbiome in rodents

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The specific location is selected based on clinical assessment and patient comfort